Arthritis preclinical platforms with humanized targets

Biomedcode offers a comprehensive collection of preclinical in vivo platforms designed for the evaluation of human biologics. Our models include both wild-type mice and mice engineered with humanized targets, such as hTNF and hTNFR1, providing highly relevant systems for translational research. We provide spontaneous chronic arthritis models as well as induced models, including the Collagen Antibody-Induced Arthritis (CAIA) model, enabling robust testing of diverse therapeutic strategies. Our platforms have a proven track record for the preclinical efficacy assessment of human biologics, small-molecule inhibitors, and combination therapies, helping researchers accelerate the development of next-generation treatments with confidence.