mRNA Analytics

Process Development: Full cGMP characterization is not always the solution when optimizing In Vitro Transcription and LNP formulation strategies. BA Sciences offers a panel of tests critical to the rapid turnaround time you need in a non-cGMP format. Common assays our clients utilize include: Size, Integrity, and Purity of mRNA constructs via capillary electrophoresis In Vitro Transcription Concentration via Nanodrop Impurity analysis (including dsRNA, pDNA, and residual protein) Polydispersity Index and Particle Size of LNP Formulations Lipid Identity via UPLC BA can help you with: Stability protocol development Commercial Release Studies Clinical Phase Stability with an emphasis on stability indicating assays Formulation Development & Optimization Stability Freeze Thaw Studies https://www.basciences.com/services/services-by-drug-form/biologics/mrna-therapeutic-testing/