Transforming Tumor Research: Engineering MHCs as Versatile Reagents
Monday, April 15, 2024 3:00 PM to 3:20 PM · 20 min. (US/Pacific)
Cell Therapy
Presentation
Room 9
Information
- In addressing solid tumors without specific biomarkers, the effectiveness of TCR-T cell therapy is hindered by the lack of reliable MHC reagents.
- To overcome this, we've developed versatile MHC molecules in different formats, such as peptide-ready, single-chain, and chimeric-MHC. These innovations offer convenient loading, enhanced sensitivity, and immunization capabilities.
- Our advancements, including fluorescent MHC-tetramers and MHC-VLPs, hold transformative potential in reshaping solid tumor studies by enabling more precise and effective R&D.