Mass photometry – an analytical technology for biomolecular characterization

Mass photometry is a single-particle analytical technology that measures the masses of biomolecules in their native states, in solution. The TwoMP mass photometer is an easy-to-use instrument that can measure masses of biomolecules between 30 kDa and 5 MDa, and requires minimal sample for analysis. In this talk, we demonstrate the utility of the TwoMP in a variety of contexts, including monitoring antibody aggregation & antigen interactions, quantifying small-molecule induced changes to complex formation, assessing sample purity and more. We also showcase the capabilities of the TwoMPAuto, a mass photometer with automated pipetting that performs measurements autonomously.