From Causes to Consequences: Decoding Off‑Target Events in CRISPR Gene Editing using INDUCE-seq
Wednesday, March 18, 2026 11:30 AM to 11:50 AM · 20 min. (Europe/London)
Gene Editing [Track 5]
Presentation
Information
- Unbiased, genome-wide mapping of gene-editing–induced DNA breaks using INDUCE-seq, a PCR-free, cell-based assay with single-nucleotide resolution.
- INDUCE-seq accelerates discovery and preclinical decision-making by delivering high signal-to-noise, reproducible on- and off-target data in days, not weeks, across therapeutically relevant cell types.
- Enables earlier de-risking of gene-editing programs, with data that supports guide selection, modality comparisons, and emerging regulatory expectations for genome integrity.
